Bombay Phenotype Blood Type
The abo blood system is further complicated by the fact that there are two subtypes of type a and two of ab. So how come your a and b types of antigens are inherited when they themselves are sugar moieties while heredity determines the proteins.
His blood is not o a b or ab but a special type called hh a rare one first discovered in bombay in 1952 and hence christened as bombay blood.
Bombay phenotype blood type. Named for the city in. The answer has to do with how we test for blood type. The four most common blood groups are a b ab and o.
Those who hold this phenotype in bombay will be only 0 01 per cent. It is mostly found in the indian sub continent india bangladesh pakistan and parts of the middle east such as iran. Someone who doesn t have a or b is assumed to be normal type o.
This blood phenotype was first discovered in bombay now known as mumbai in india by dr. First found in bombay mumbai in india hence called bombay blood group. Hh or the bombay blood group is a rare blood type.
4 bombay blood group known as oh or. As outlined here the h antigen is made by adding a fucose sugar to an oligosaccharide and that must happen before either a or b antigens can be made i e if you can t make h you can t make a or b. They also don t have the a antigen or b antigen.
Bombay o h phenotype the lack of a b or h antigens on red blood cells and in secretions and plasma. Blood types common rare. They are only looking for a and b.
If the parent has bombay blood type blood then there is a possibility that the child blood type will also be hh. The bombay phenotype was first reported by bhende 1952 in bombay india. Transfusion with bombay blood type.
Over the last two weeks the bombay blood group a rare blood type has been at the centre of attention in mumbai s healthcare scene. Bombay blood phenotype was first discovered in bombay. Blood tests don t look for the h antigen.
Bombay blood group is the rarest blood group. These are referred to as a 1 a 2 a 1 b and a 2 b. But the youngster has a very rare blood type.
So the blood test simply can t. This seemingly impossible phenotype result has been referred to as a bombay phenotype because it was first described in that indian city. Demand for the blood type has coincidentally spiked at hospitals but supply has been scarce.
This very rare phenotype is generally present in about 0 0004 about 4 per million of the human population though in some places such as mumbai formerly bombay locals can have occurrences in as much as 0 01 1 in 10 000 of inhabitants. Before understanding bombay blood group you need to know how the abo blood group system forms its antigens which are a b and one more that people often dont know is h. People in the bombay blood group don t have the h antigen.
In india by dr.
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